What is apigenin and where can it be found?<\/h2>\n
Apigenin<\/strong> is a natural flavonoid, belonging to the polyphenol family, found mainly in fruits and vegetables. You can find it in notable quantities in parsley, celery, onions, chamomile, thyme, oregano, basil, as well as in certain beverages like tea, beer, and wine.<\/p>\n If you wish to delve deeper into the subject of apigenin, I invite you to consult our detailed article that explains in depth its molecular composition and biochemical properties.<\/p>\n But what particularly interests us today is its anti-aging potential…<\/p>\n Apigenin<\/strong> combats aging primarily by increasing NAD+ levels in our body, an essential molecule that naturally decreases with age.<\/p>\n This action is complemented by powerful anti-inflammatory and antioxidant effects that together help slow down the aging process.<\/p>\n You might be wondering what NAD+ is? It’s a molecule (nicotinamide adenine dinucleotide) that plays a crucial role in our cells’ energy production. Imagine it as a rechargeable battery that powers your cells! Unfortunately, with age, our NAD+ levels drop significantly, affecting our energy and vitality.<\/p>\n Apigenin<\/strong> would help maintain these levels by inhibiting an enzyme called CD38, which usually consumes NAD+. At the mitochondrial level (the powerhouses of our cells)<\/em>, apigenin<\/strong> does a remarkable job. Not only does it improve their function, but it also helps protect them from age-related damage.<\/p>\n Chronic inflammation and oxidative stress are two other aspects of aging that apigenin<\/strong> already effectively combats. It acts like a firefighter extinguishing small inflammation fires in your body while neutralizing free radicals that can damage your cells.<\/p>\n Let’s see what scientific studies tell us…<\/p>\n Research on apigenin<\/strong> shows particularly promising results in animal studies, especially regarding longevity and age-related diseases. However, there is currently a caveat, as clinical studies in humans remain limited, although the initial results are encouraging.<\/p>\n Researchers have conducted fascinating studies on different animal models. For example, in C. elegans worms (a commonly used research organism)<\/i>, administration of apigenin<\/strong> at a concentration of 200-400 \u03bcg\/mL significantly increased their lifespan.<\/p>\n It also improved their resistance to oxidative stress (something already known for Apigenin) by regulating the expression of several important aging-related genes.<\/p>\n In mice, the results are equally interesting. A study showed that apigenin, administered orally at 300-900 mg\/kg, improved learning and memory in aged mice<\/strong>. Researchers also observed protection against oxidative damage and improved cerebral blood flow.<\/p>\n On the clinical studies side, research primarily uses chamomile extract, which contains about 5% to 25% apigenin<\/strong>.<\/p>\nHow does apigenin act on aging?<\/h2>\n
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<\/figure>\nWhat do scientific studies tell us about apigenin?<\/h2>\n
Animal studies<\/h3>\n
Human studies<\/h3>\n
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