Composition and dosage
Ingredients
-
NICOTINAMIDE RIBOSIDE 300 mgNicotinamide Riboside Chloride (NR)
-
VITAMIN B3 54 mgNicotinamide (Classic form)
-
NADH 25 mgNicotinamide Adenine Dinucleotide Reduced (Protected by DRcaps®)
Dosage
Recommended serving: 2 capsules
Certificates of analysis
NAD+ : Benefits and virtues
Prolonged Action with NR and Vitamin B3
Unlike NADH, which is directly available, Nicotinamide Riboside (NR) acts as a precursor to NAD⁺. Once absorbed, it is gradually converted into Nicotinamide Mononucleotide (NMN) through the action of the enzyme Nicotinamide Riboside Kinase (NRK). Then, NMN is transformed into NAD⁺ by NMN adenylyltransferase (NMNAT). This process takes more time, but it allows for a continuous and sustained release of NAD⁺, ensuring a prolonged supply of cellular energy and better metabolic regeneration over several hours.- Improvement of physical performance, particularly sports endurance, through optimization of cellular energy production. NAD⁺ plays a key role in energy metabolism by facilitating the conversion of nutrients into ATP.
- Optimization of metabolism. Adequate levels of NAD⁺ promote efficient cellular metabolism.
- Potential slowing of cellular aging. By supporting DNA repair and sirtuin activity.
- Brain: improvement of brain functions and protection against neurodegeneration.
- Vascularization: increase of neovascularization, capillary density, and blood flow.
- Liver: improvement of liver function, reduction of hepatic steatosis.
- Muscles: reduction of atrophy, improvement of mitochondrial function.
- Adipose tissue: reduction of dyslipidemia and prevention of insulin resistance.
- Inflammation: reduction of inflammation and improvement of immune cell function.
- Synergy of 3 active ingredients
- Optimization of the NADH/NAD+ ratio
- Fast and prolonged action
- 3 NAD+ metabolism pathways
- Gastro-resistant capsules
TEN: Always at the forefront of innovation. We have designed an advanced formula that effectively optimizes your NAD⁺ levels while maximizing its benefits on cellular and energy metabolism. Our supplement rapidly and sustainably increases NAD⁺, while ensuring an optimal balance between NAD⁺ and NADH, essential for proper cellular function.
NR, NADH and Vitamin B3 take distinct metabolic pathways to increase NAD⁺ levels, ensuring a rapid rise, but also a medium and long-term increase.
1. Nicotinamide Riboside (NR): Direct precursor that follows the salvage pathway.
2. NADH: Reduced form of NAD⁺, involved in immediate energy production and the redox cycle.
3. Nicotinamide (Niacinamide): Follows the salvage pathway via the action of NAMPT.
We have chosen DRCAPS gastro-resistant capsules to protect NADH from stomach acidity and ensure optimal absorption of active ingredients like NR. Thanks to this technology, the release is delayed until the small intestine, where absorption is most effective.
NAD⁺ is the oxidized form of NAD, and its main role is to act as an electron acceptor (glycolysis, Krebs cycle, DNA repair). NADH is the reduced form of NAD⁺. It plays an essential role in energy metabolism by transporting electrons to the mitochondria to produce ATP.
NMN (Nicotinamide Mononucleotide) is no longer authorized for sale in Europe (Novel Food). However, its alternative, NR (Nicotinamide Riboside), remains authorized and available. Studies show that both are capable of effectively increasing NAD⁺ levels.
Customer Reviews and Tests
Studies and Scientific References
Scientific sources (18)
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- nature.com
- nature.com
- pubmed.ncbi.nlm.nih.gov
- science.org
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- nature.com
- pubmed.ncbi.nlm.nih.gov
- nature.com