Ecdysteroids: Muscular and hormonal balance
Are you struggling to reach a milestone in your muscular development, despite a strict diet and intense training?
Ecdysteroid could well be the lever you're looking for. Derived from plants such as Ajuga turkestanica, these fascinating natural compounds are attracting growing interest for their effects on muscle mass and sports performance.
Find out in this article about their proven mechanisms of action, their real benefits for protein synthesis, and why their natural status makes them an interesting alternative to conventional supplements.
- Mechanism of action Ecdysteroids activate beta-oestrogen receptors, stimulating protein synthesis without disrupting natural hormones.
- Natural origin Ecdysterone comes from Cyanotis arachnoidea, while turkesterone is extracted from Ajuga turkestanica.
- Muscular benefits These compounds promote muscle growth, strength and recovery, without the side-effects of conventional steroids.
- Effect on aromatase Ecdysteroids help regulate aromatase, thereby reducing the excess oestrogen associated with body fat.
- Safety and legality Non-doping and well tolerated in moderate doses, they are authorised for use in competition and have few known side-effects.
What is an ecdysteroid and how does it work?
Ecdysteroids are naturally occurring steroid compounds that mimic insect molting hormones. Although they share a molecular structure similar to human steroid hormones, they do not act as anabolic steroids. These molecules, including ecdysterone and turkesterone, are mainly extracted from traditional medicinal plants. Their interest lies in their ability to interact with human metabolic pathways without directly disrupting endogenous hormone production.
Two plants are of particular interest to ecdysteroid users: theAjuga turkestanica for its turkesterone content, and Cyanotis arachnoidea known for its ecdysterone-rich extract. These phytoecdysteroids are part of a wider family of natural compounds found in certain plant species. Although they are present in small quantities in foods such as spinach, only concentrated extracts can be used to produce biologically active doses.
Mechanisms of action of ecdysteroids in the human body
Interaction with hormone receptors
Ecdysteroids interact primarily with oestrogen beta receptors. Their activation triggers a process that stimulates muscle protein synthesis. Contrary to popular belief, these compounds do not become steroid hormones in the body, but create an environment conducive to anabolism. Discover the key differences between these two molecules here.
| Features | Ecdysterone | Turkesterone |
|---|---|---|
| Molecular structure | 6 hydroxyl groups | 7 hydroxyl groups |
| Resistance to metabolic degradation | Moderate | High |
| Interaction with hormone receptors | Binds specifically to β-estrogen receptors | Structure similar to testosterone, no specific interaction with oestrogen receptors |
| Potential anabolic effect | Demonstrated in comparative studies with other anabolic steroids | Preliminary studies suggest increased power for muscle growth |
By activating oestrogen beta receptors, a balance is achieved between testosterone and oestrogen. This subtle mechanism does not suddenly increase hormone levels, but promotes a more balanced functioning of the endocrine system. Unlike anabolic steroids, ecdysteroids do not alter the natural production of hormones but rather optimise their use.
Effects on aromatase
Aromatase catalyses the conversion of testosterone into oestrogen. This enzyme, found in adipose tissue in particular, plays a central role in hormone metabolism. Its activity increases with excess body fat, modifying the testosterone/estrogen ratio.
Adipose tissue is a major site of aromatase activity. In overweight people, this enzymatic overactivity leads to an increase in oestrogen, favouring the development of gynaecomastia. By acting on these mechanisms, ecdysteroids can help to reduce the risk of gynaecomastia. better regulation of aromatase without steroid side effects.
Variability of individual responses
Your sensitivity to ecdysteroids depends on your initial hormonal balance. People with naturally low levels of oestrogen generally show better responses. However, some people with higher levels have also seen notable progress.
The differences in effectiveness can be explained by a number of factors. In addition to the hormonal basis, genetics, quality of sleep, and the precision of the dosage influence the results. This aspect explains why some users describe spectacular effects while others note little change, despite a similar protocol.
Ecdysterone: a shake-up in the world of sport?
If you want to delve deeper into the subject (and believe me, it's worth it), we highly recommend our dedicated article: Ecdysterone: a muscular secret from the East?. You'll discover all the ins and outs of this fascinating molecule. (Prepare to be surprised!)
Proven and potential benefits of ecdysteroids
Improving sporting performance
Scientific evidence shows that ecdysteroids, particularly ecdysterone, stimulate muscle growth and strength. One study showed greater muscle mass gains in volunteers taking 12 mg/d of ecdysterone. To find out more about premium quality turkesteroneSee our detailed product sheet.
- Stimulates muscle protein synthesis
- PTO acceleration and muscle mass
- Better recovery post-training
- Overall improvement physical performance
Compared with ecdysterone, turkesterone appears to be more potent, according to some preliminary studies. Data on humans is still limited, but animal trials have shown that turkesterone is more potent than ecdysterone. show gains in muscle mass between 3.6 and 5.4 kg in 8 weeks. The anabolic effects are well documented for ecdysterone, unlike turkesterone, for which there is a lack of robust yet very encouraging research.
Effects on muscle mass
Ecdysteroids activate muscle protein synthesis pathways by interacting with hormone receptors. This stimulation results in measurable increase in muscle massThis is particularly noticeable in athletes following structured protocols.
Research shows that ecdysteroids surpass some natural anabolic supplements in effectiveness. One comparative study showed bench press and squat performances significantly improved with ecdysterone. The effects vary according to individual sensitivity, linked to basic hormonal balance and genetics.
Reducing body fat
Studies on rats show that 20-hydroxyecdysterone limits intake visceral fat. This benefit was observed even in conditions of caloric surplus, suggesting an interesting metabolic effect.
Animal research indicates that supplementation with 20-hydroxyecdysterone reduce storage fats. In a 13-week protocol, the treated rodents gained 20% less weight than the control group despite eating a high-fat diet. These results have yet to be confirmed in humans.
Effects on metabolic health
Ecdysteroids influence carbohydrate metabolism by reducing hepatic glucose production. This action is similar to that of anti-diabetic treatments, suggesting that it could be of interest to people with pre-diabetes.
The effects on metabolism in post-menopausal women remain poorly documented. Animal studies indicate a regulation of adipose deposits and an improvement in carbohydrate metabolism. The precise mechanisms remain to be explored, but the outlook is promising.
Practical aspects and safety considerations
Legal status and doping issues
Ecdysteroids are not on the World Anti-Doping Agency's list of banned substances. Their status as a natural complement makes them accessible to athletes in competition, with the exception of professional leagues with specific internal regulations.
Unlike anabolic steroids, ecdysteroids do not directly increase testosterone. Their mode of action on hormone receptors differs from that of anabolic steroids. fundamentally different from conventional steroidswhich explains their legal tolerance in top-level sport.
Food sources and supplements
Ecdysteroids are found naturally in foods such as spinach, mushrooms and arrowroot. However, concentrations are so low that it would be necessary to consume unrealistic quantities to obtain significant metabolic effects.
Opt for our ecdysterone DIX when choosing a supplement. Reliable products indicate precisely the dosage of ecdysterone per capsule and the dosage method used (HPLC). Transparency about the plant source and purity tests is essential.
Warning against fake products
The market is full of mislabelled or contaminated supplements. Recent analyses reveal that 89% labels are incorrect. Some products contain prohibited substances that are not mentioned on the packaging.
Learn how to identify the signs of a counterfeit product. Check for certificates purity, transparency of extraction processes and the manufacturer's reputation. Avoid offers that are too tempting or that lack clear scientific documentation.
Potential side effects
Studies with ecdysterone 800 mg/day did not show any no major side effects. However, some sensitive individuals may experience temporary digestive problems, particularly with doses above 1500 mg.
Tolerance varies according to individual profile. The users experiencing unusual reactions should discontinue use and consult a healthcare professional. Pregnant or breast-feeding women, as well as minors, should avoid these supplements in the absence of sufficient data.
Recommendations for use
Ecdysteroids are mainly aimed at experienced sportspeople looking to optimise their progress. Their effectiveness can be seen in fully with structured training and a suitable diet.
To maximise the benefits, combine your supplementation with appropriate strength training. Assess your progress over 8 to 12 weeks with objective measurements of strength and muscle mass.
Future prospects and final considerations
Current state of research
Scientific data on ecdysteroids remains limited, particularly on turkesterone. Most robust studies on ecdysterone date back to the twentieth century. The lack of recent, controlled research on humans hinders a complete understanding of their mechanism of action.
The major gaps concern optimal dosage, long-term effects and safety of use. The rare human trials show promising results but still lacking methodological rigour. Anecdotal evidence abounds, but the scientific community is calling for more proof.
Integration into future sports nutrition
Ecdysteroids could evolve as natural hormone regulators. Their action on the testosterone/estrogen ratio opens up new perspectives for hormone regulation without steroidal effects. Their place in sports nutrition will depend on future research into their real effectiveness.
Future studies could explore their synergy with other supplements. Aromatase modulation is a particular area of interest for body composition issues. Their non-doping status positions them as serious candidates sports use framed.
Expected scientific developments
Research should focus on optimising molecular forms to improve bioavailability. Controlled studies in humans are needed to establish specific recommendations. The regulatory framework provided by sports federations will remain a topical issue.
The future will probably bring more effective formulations, thanks to research into ecdysteroid derivatives. Studies into the metabolic effects of ecdysteroids, particularly in pre-diabetic populations, should be stepped up. Standardisation of extraction and analysis methods guarantee reliability products on the market.
Ecdysteroids, such as ecdysterone and turkesterone, provide a natural hormonal balance and a natural stimulation of protein synthesis to boost your muscle mass. Their action on aromatase and adipose deposits makes them a relevant choice for optimising your performance. Why not make them part of your routine, while paying attention to the quality of the products? Your body deserves to explore these anabolic allies, without compromising on health. Your next session could be the start of a major change.
The power of ecdysteroids DIX: Turkesterone and Ecdysterone
At DIX, we are proud to offer you two of the most promising ecdysteroids for improving performance and muscle development: the Turkesterone and theEcdysterone.
Our Turkesterone, standardised at 25%and our Ecdysterone at 98%are the result of state-of-the-art extraction and filtration processes.
To maximise their absorption, we've combined them with Hydroxypropyl Cyclodextrin Complex and black pepper extract, doubling their bioavailability.
With 700 mg per capsule, you benefit from optimum concentration to stimulate protein synthesis, increase muscle fibre density and improve your adaptation to metabolic stress.
Whether you choose Turkesterone or Ecdysterone, or combine them for even more impressive results, you can count on the superior quality and effectiveness of our laboratory-tested products for your peace of mind.
